APPLICATION OF BIOINFORMATICS IN THE DRUG DISCOVERY

Abstract

The construction of this paper is to provide information about the present scenario in the field of bioinformatics. The main aim is to show the implication of the subject in the field of drug discovery in modern medicine. Discussion contains the topics such as the basics of bioinformatics, subjects involved and the procedural implementation of the subject in drug discovery. In the beginning the discussion is made about the challenges faced by pharmaceutical companies in drug designing, the effect of bioinformatics in the steps of virtual screening, the various other steps which come under the virtual screening. Further the contents discuss the selection of the particular steps, the various other computational docking and algorithmic tools used till date. Discussion continues by stating the few examples about successful implementations of computation biology in drug designing and identification of genetic disorders. The challenges found are right from mutation of the disease-causing pathogens to the resistance they form against the drug, lack of availability of the software to store the genomic data, and the qualification of the computational analyst/chemist who interprets the results. In the conclusion the points are discussed about the requirement of application of computational procedures in the other fields of medicine other than allopathy.